丁香国际医疗海外咨询What Is the Shelf Life of Plerixafor (释倍灵普乐沙福)? Key Storage & Usage Guidelines
What Is the Shelf Life of Plerixafor (释倍灵普乐沙福)? Key Storage & Usage Guidelines
For patients undergoing stem cell transplantation for multiple myeloma or lymphoma, Plerixafor (释倍灵普乐沙福, brand name: Mozobil) plays a crucial role in mobilizing stem cells from the bone marrow. However, many patients have questions about how long this medication remains effective and how to store it properly. This article provides a detailed guide on Plerixafor’s shelf life, storage requirements, and safe usage to ensure optimal treatment outcomes.
What Is Plerixafor (释倍灵普乐沙福) Used For?
Plerixafor is a CXCR4 chemokine receptor antagonist that helps:
Increase stem cell release from bone marrow into the bloodstream
Support stem cell collection for transplantation in multiple myeloma and lymphoma patients
Improve treatment success for those who do not respond well to conventional therapies
Because of its specialized use, proper storage and adherence to the expiration date are essential for maintaining effectiveness.
What Is the Shelf Life of Plerixafor?
Standard expiration period: 36 months (3 years) from the manufacturing date.
Varies by batch: Always check the label or packaging for the exact expiry date.
Do not use expired medication: Expired Plerixafor may lose potency, reducing treatment efficacy.
How to Check the Expiry Date?
Look for the "EXP" date on the original packaging.
Confirm with the pharmacy or healthcare provider if unsure.
Avoid using if the medication has been stored improperly (e.g., exposed to heat or moisture).
Proper Storage Conditions for Plerixafor
To maintain effectiveness, Plerixafor must be stored under specific conditions:
✔ Temperature: Keep at 2°C–8°C (36°F–46°F) in a refrigerator.
✔ Protect from light: Store in the original packaging to avoid exposure.
✔ Avoid freezing or excessive heat: Do not leave at room temperature for extended periods.
If refrigeration is unavailable temporarily (e.g., during travel):
Use a cooler with ice packs for short-term storage.
Return to proper refrigeration as soon as possible.
Cost & Accessibility Considerations
Plerixafor is a specialized and expensive medication, which makes proper storage even more critical to avoid waste.
Insurance coverage varies: Some plans may require prior authorization.
Discuss alternatives with your doctor if cost is a concern.
Safety & Usage Tips
While Plerixafor is generally well-tolerated, possible side effects include:
Nausea, dizziness, or injection-site reactions
Low platelet counts (thrombocytopenia)
Allergic reactions (rare but serious)
To ensure safe use:
✔ Follow the doctor’s prescribed dosage and schedule.
✔ Monitor for unusual symptoms and report them immediately.
✔ Keep follow-up appointments for blood tests and progress checks.
Q&A: Common Patient Concerns
Q1: What happens if I accidentally use expired Plerixafor?
A: Expired medication may not work as effectively, potentially compromising stem cell collection. Always check the expiry date before use.
Q2: Can I store Plerixafor at room temperature?
A: No. It must be refrigerated (2°C–8°C). Short-term exposure (e.g., during transport) is acceptable, but prolonged room-temperature storage can degrade the drug.
Q3: How do I know if my Plerixafor has gone bad?
A: Check for changes in color, particles, or unusual odor. If in doubt, consult your pharmacist or doctor before using.
Final Advice
Understanding Plerixafor’s shelf life and storage requirements helps ensure the medication remains effective and safe throughout treatment. Always:
✔ Check the expiration date before use.
✔ Store properly in a refrigerator.
✔ Follow medical guidance for administration.
If you have further questions, consult Dingxiang Medical Service for professional support.
English Translation
What Is the Shelf Life of Plerixafor (释倍灵普乐沙福)? Key Storage & Usage Guidelines
Plerixafor (释倍灵普乐沙福, brand name: Mozobil) is used for stem cell mobilization in multiple myeloma and lymphoma patients. Its shelf life is 36 months, but proper storage (2°C–8°C) is crucial to maintain effectiveness.
Key Points:
Expiry date varies by batch – Always check the label.
Refrigeration required – Avoid heat, light, and freezing.
Do not use expired medication – It may lose potency.
Consult your doctor or pharmacist if unsure about storage or usage.
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