Are the Side Effects of Mepolizumab Significant?

Are the Side Effects of Mepolizumab Significant?

Mepolizumab is a medication used to treat severe asthma, allergic rhinitis, and parasitic infections. It is a monoclonal antibody that targets and destroys white blood cells in the body, thereby reducing inflammatory responses. Compared to traditional corticosteroids, mepolizumab offers advantages such as rapid response and fewer side effects. However, it is important to be aware of its potential side effects, which are detailed below.

1. Allergic ReactionsMepolizumab is a large protein molecule that can trigger an immune response in the body. After injection, some patients may experience allergic reactions, characterized by symptoms such as facial swelling, skin itching, shortness of breath, and abdominal pain and diarrhea. In severe cases, these reactions can be fatal. Therefore, it is crucial to ensure that patients have no history of allergies before using the drug.

2. Abnormal Liver FunctionSome patients may experience side effects related to abnormal liver function after treatment with mepolizumab, such as jaundice and elevated liver enzymes. This may occur because mepolizumab can affect the liver's metabolism and excretion of drugs, leading to liver dysfunction. In such cases, it is necessary to seek medical attention promptly and discontinue the medication.

3. Headache and NauseaDuring treatment with mepolizumab, some patients may experience discomfort symptoms such as headache and nausea. This may be due to the drug's effects on the nervous system. If these symptoms are severe, it is important to consult a doctor for appropriate management and adjustment of the treatment plan.

4. Increased Risk of InfectionThe use of mepolizumab may weaken the patient's immune system, thereby increasing the risk of infection. Therefore, during the course of treatment, it is essential to pay special attention to personal hygiene and infection prevention measures, such as frequent handwashing and avoiding crowded places.

In summary, while mepolizumab does have some side effects, they are relatively minor compared to those of other disease-treating medications, and it is generally considered safe. Before using it, it is necessary to understand the patient's medical condition, allergy history, and overall health status. Treatment should be administered by a professional doctor based on the patient's specific situation. Additionally, during the use of mepolizumab, any discomfort symptoms should be reported to the doctor promptly for timely management.