丁香国际医疗海外咨询Ramucirumab (Cyramza) Price in China: A Comprehensive Guide
Ramucirumab (Cyramza) Price in China: A Comprehensive Guide
Ramucirumab (brand name Cyramza) is a novel targeted therapy drug widely used for treating gastric cancer and colorectal cancer. As a VEGFR-2 inhibitor, it blocks tumor angiogenesis by targeting the vascular endothelial growth factor receptor, thereby cutting off blood supply to tumors and inhibiting their growth and metastasis. In China, ramucirumab is recognized as an effective and safe treatment for these cancers.
1. Mechanism of Action
Ramucirumab is an anti-angiogenic drug that binds to VEGFR-2, preventing the formation and growth of tumor blood vessels. By suppressing VEGF signaling, it reduces vascular permeability and new blood vessel development, ultimately starving tumors of nutrients and oxygen.
2. Clinical Applications
Approved uses in China:
Gastric cancer (first-line & later-line therapy)
Colorectal cancer
Clinical benefits:
Significantly improves progression-free survival (PFS) and overall survival (OS) compared to traditional chemotherapy.
Enhances treatment efficacy and prognosis.
3. Price in China
The cost of ramucirumab varies based on:
Dosage (weight-based, typically 8 mg/kg every 2 weeks)
Treatment duration
Healthcare facility
Estimated price range:
Tens of thousands to over 100,000 RMB per course (subject to fluctuations).
For reference: The U.S. Lilly version (~100mg/10ml x 2 vials) costs ~8,000 RMB per box. A 70kg patient may require 3 boxes per dose (24,000 RMB per infusion).
Note:
Prices may vary due to exchange rates, insurance coverage, and hospital policies.
Patients should consult their doctor/pharmacist for exact pricing and reimbursement options.
4. Side Effects & Precautions
Common side effects:
Hypertension
Bleeding tendencies
Fatigue
Important guidelines:
Strictly follow the prescribed dosage and schedule.
Monitor for adverse reactions and report them promptly.
Regular blood tests and imaging are required during treatment.
Conclusion
Ramucirumab represents a breakthrough treatment for gastric and colorectal cancers in China, despite its high cost. Patients should:
Consult specialists for personalized treatment plans.
Check insurance coverage and financial aid programs.
Adhere to medical supervision to maximize benefits and minimize risks.
Key Terms in Bold:
Ramucirumab (Cyramza)
VEGFR-2 inhibitor
Gastric/colorectal cancer
Price: 10,000–100,000+ RMB
Side effects: hypertension, bleeding, fatigue
